The City College of New York
Phone: (212) 650-7031
Biomolecules, peptide-nucleotide interactions, self-assembly, microrheology.
RAYMOND TU, an assistant professor of chemical engineering at The City University of New York, earned a BS from the University of Florida and a PhD from the University of California-Santa Barbara.
Nature has evolved the ability to self-assemble molecules into functional architectures capable of specifically binding a diverse set of ligands. Our research program aspires to mimic aspects of this process by designing a set of peptide-based building blocks, which are multifaceted molecules conjugating elements that direct assembly to components that are responsible for specific binding interactions. Compared to "top-down" approaches, such as lithography, programming molecules to self-assemble allows one to access complex structures in a parallel fashion, yielding faster kinetics for practical processing at nanometer length-scales. The design and application of such "bottom-up" assemblies requires precision synthesis, predictive folding algorithms and accurate characterization of self-assembly. This methodology is proving to be an effective tool for engineering drug-delivery vehicles, biosensing and molecular medicines.