Optical Biopsy

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Diagnosing Tissue with Light

Researchers in the Mediphotonics Laboratory at City College have developed a fluorescence-based optical biopsy system that uses the properties of light and its interaction with materials to provide a powerful tool to aid in the diagnosis of cancer. Optical biopsy can offer physicians significant advantages over traditional pathological measurements. The method is non-invasive and uses non-ionizing radiation to probe for tumors without damaging health tissue.

Potential Applications: to 19
Endoscopic-based probes:

  • Esophagus
  • Stomach
  • Colon
  • Intestines
  • Lungs
  • Gynecological Tract

Stereotactic needle based probes:

  • Breast
  • Prostate
  • Kidney

Other Areas:

  • Aerodigestive Tract
  • Operating Room


  • Non-invasive. No tissue removal required.
  • Rapid measurements with real time results.
  • High spatial resolution to detect small tumors.
  • Fluorescence imaging to clearly define tumorous regions.
  • Potential to detect precancerous conditions.