Paul Gottlieb

Paul Gottlieb

Assistant Professor
Department of Microbiology and Immunology
The City College of NY
138th Street and Convent Avenue
New York, NY 10031
Tel: (212) 650-7709
pgottl@med.cuny.edu

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Education

The City University of NY

Ph.D. Molecular Biology

1984

State University of New York at Stonybrook

B.Sc. Biology

1974


Professional Experience 

Assistant Professor

CCNY, Depts of Biology and Biochemistry

1997 - Present

Patent Examiner

U.S. Patent and Trademark Office

1996 - 1997

Senior Research Scientist

National Institutes of Health

1995 - 1996

Director

Dept of Virus Inactivation, NY Blood Center/Melville Biologics Inc.

1993 - 1995

Research Associate

Public Health Research Institute of the NY

1984 - 1993

Adjunct Lecturer/Graduate Fellow

Dept of Microbiology,Hunter College School of Nursing

1978 - 1984


Selected Publications

  • Crystallization and X-ray diffraction analysis of bacteriophage f 12 packaging fidelity factor P7. Kainov, D.E, Simonov, V., Bamford, D.H., Tuma, R., Gottlieb, P.,  Wei, H., Walsh, M., Belrhali, H., and Merckel, M.C., Acta Crystallographica Section D  in press, 2004.
  • Virus particles monitored by fluorescence spectroscopy: a potential detection assay for macromolecular assembly. Alimova, A., Katz, A., Podder, R., Minko, G., Wei, H., Alfano, R.R., and Gottlieb, P.,  Photochem Photobiol 80, 41-46, 2004. 
  • Expression of the Epstein-Barr Virus Nuclear Antigen-1 (EBNA-1) in the mouse can elicit the production of anti-dsDNA and anti-Sm antibodies. Sundar, K., Jacques, S., Gottlieb, P., Villars, R., Benito, M-E., Taylor, D.K., and Spatz, L.A., J. Autoimmunity 23, 127-140, 2004.
  • Production, crystallization, and preliminary X-ray cystallographic studies on the bacteriophage f 12 packaging motor.  Mancini, E., Kainov, D.E., Wei, H., Gottlieb, P., Tuma, R., Bamford, D.H., Stuart, D.I., and Grimes, J.E., Acta Crystallographica Section D, Biological Crystallography 60 (Pt 3), 588-590, 2004.
  • Temperature requirements for the initiation of RNA-dependent RNA polymerization.  Yang, H., Gottlieb, P., Wei, H., Bamford, D., and Makeyev, E.V., Virology 314, 706-715, 2003.
  • Characterization of f 12, a bacteriophage related to f 6: nucleotide sequence of the small and middle double-stranded RNA. Gottlieb, P., Wei, H., Potgieter, C.,  and Toporovsky, I., Virology 293, 118-124, 2002a.
  • Characterization of f12, a bacteriophage related to f6: nucleotide sequence of the large double-stranded RNA. Gottlieb, P., Potgieter, C., Wei, H., and Toporovsky, I., Virology 295, 266-271, 2002b.

Selected Patents

  • Methods of use of phthalocyanines to inactivate blood borne parasites.  Gottlieb, P., Ben-Hur, E. and Lustigman, S., inventors, New York Blood Center, assignee, (1998), Patent #5,912,241.
  • Methods of use of phthalocyanines to inactivate blood borne parasites.  Gottlieb, P., Ben-Hur, E. and Lustigman, S., inventors, New York Blood Center, assignee, (1997), Patent #5,985,331.

Grants Received

  • CAREER: Integrated Study and Research in Virology, NSF, 2000 - 2004, $100,000
  • Characterization of the anti-dsDNA response in mice expressing, EBNA-1 NIH/RCM,I 2002 - 2005, $75,000
  • Complexity Issues in the Modeling of the Transport of Aerosol Aggregates, The Rockefeller Brothers Fund, 2003 - 2004, $25,000
  • Establishment of an Epstein-Barr Virus (EBV)-Based Vector Model to Determine the Etiology of Systemic Lupus Erythematosus (SLE) PSC-CUNY 2003 - 2004 $3,103
  • Analysis of the cystovirus polymerase complex, PSC-CUNY, 2003 - 2004, $3,423