Professor
Department of Chemistry and Biochemistry
Hunter College of CUNY
695 Park Ave
New York NY 10021
Phone: (212) 650-3791 Fax: (212) 772-5332
Email: cdrain@hunter.cuny.edu
Download Print Version <pdf>
Education
|
Tufts University
|
Ph.D.
|
1988
|
|
University of Missouri
|
BA
|
1981
|
Professional Experience
|
Professor
|
Hunter College
|
2004 - Present
|
|
Associate Professor
|
Hunter College
|
2000 - 2004
|
|
Assistant Professor
|
Hunter College
|
1996 - 1999
|
|
Adjunct Faculty
|
The Rockefeller University
|
1996 - Present
|
|
Lab Director
|
Midco Products, Inc., St. Louis
|
1981 - 1984
|
Research Interests
Self-assembly and self-organization discrete arrays and films. Design, synthesis, characterization, and biological activities of porphyrinoid compounds - especially a photodynamic therapeutics (PDT). This is also an integrated project that entails chemistry, biology, and spectroscopy. We have discovered a series of new compounds that are significantly better than the current FDA approved technology. Nanoparticles of some of these macrocyles serve as drug delivery agents and in vivo biological sensors.
Selected Publications
- Photodynamic Therapy Using Carbohydrate Conjugated Porphyrins X. Chen and C.M. Drain, Drug Design Reviews - Online, 2004, 1(3), 215-234. Bentham Science Publishers Ltd.
- Efficient Synthesis and Photodynamic Activity of Porphyrin-Saccharide Conjugates: Targeting and Incapacitating Cancer Cells X. Chen, L. Hui, D. A. Foster, C. M. Drain, 2004, 43, 10918-10929.
- Synthesis of Gradient Copolymer Brushes via Surface Initiated Atom Transfer Radical Copolymerization C. Xu, T. Wu, C. M. Drain, J. D. Batteas, K. L. Beers ACS Polymer Reprints, Fall, 2004.
- Organizing Self-Assembled Porphyrin Arrays On Metal And Glass Surfaces C.M. Drain, T. Milic, J. C. Garno, G. Smeureanu, J.D. Batteas ACS Polymer Reprints 2004, 45(1), 346-347.
- Self-Organization of Self-Assembled Tetrameric Porphyrin Arrays on Surfaces T. Milic, J. C. Garno, G. Smeureanu, J. D. Batteas, C. M. Drain, Langmuir, 2004, 20, 3974-3983.
- Self-assembled Porphyrin Arrays on Surfaces C.M. Drain, G. Smeareanu, J.D. Batteas, S. Patel. Book chapter: Dekker Encyclopedia of Nanotechnology, Vol 5. pp3481-3502. J.A. Schwartz, C.I. Contescu, K. Putyera, Eds.; Marcel Dekker, Inc. New York, 2004.
- A Bench Top Method for the Fabrication and Patterning of Nanoscale Structures on Polymers J. M. Helt, C. M. Drain, J. D. Batteas, J. Am. Chem. Soc. 136, 2004, 628-634.
- Self-Assembled Porphyrinic Nanoarchitectures C.M. Drain, X. Chen. Book chapter: Encyclopedia of Nanoscience & Nanotechnology Vol. 9, pp593-616. H.S. Nalwa Edt., American Scientific Press, 2004.
Grants
- Conbinatorial Chemistry of Porphyrins, NIH 2004 (SCORE) $550K
- fellowship for graduate student Chang Xu N.I.S.T. 2004:$8K
- Porphyrin Therapeutics, PSC-CUNY 2003 $4K
- fellowship graduate N.S.F.-N.I.S.T. 2004 $6.6K
- Self-Assembled Phonic Materials N.S.F. 2002 $360K
- Binational Science Foundation, with Israel Goldberg Israel-US 2000: $240K
- Interdisciplinary Graduate Education Training Research, N.S.F. 1999: IGERT Co-PI ~$1000K/year, 4 years for HC, ~$3.5M for the program
