Charles Michael Drain

Charles Michael DrainProfessor
Department of Chemistry and Biochemistry
Hunter College of CUNY
695 Park Ave
New York NY 10021
Phone: (212) 650-3791 Fax: (212) 772-5332
Email: cdrain@hunter.cuny.edu

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Education

Tufts University

Ph.D.

1988

University of Missouri

BA

1981


Professional Experience

Professor

Hunter College

2004 - Present

Associate Professor

Hunter College

2000 - 2004

Assistant Professor

Hunter College

1996 - 1999

Adjunct Faculty

The Rockefeller University

1996 - Present

Lab Director

Midco Products, Inc., St. Louis

1981 - 1984


Research Interests

Self-assembly and self-organization discrete arrays and films.  Design, synthesis, characterization, and biological activities of porphyrinoid compounds - especially a photodynamic therapeutics (PDT). This is also an integrated project that entails chemistry, biology, and spectroscopy. We have discovered a series of new compounds that are significantly better than the current FDA approved technology. Nanoparticles of some of these macrocyles serve as drug delivery agents and in vivo biological sensors.

Selected Publications

  • Photodynamic Therapy Using Carbohydrate Conjugated Porphyrins X. Chen and C.M. Drain, Drug Design Reviews - Online, 2004, 1(3), 215-234. Bentham Science Publishers Ltd.
  • Efficient Synthesis and Photodynamic Activity of Porphyrin-Saccharide Conjugates: Targeting and Incapacitating Cancer Cells X. Chen, L. Hui, D. A. Foster, C. M. Drain,  2004, 43, 10918-10929.
  • Synthesis of Gradient Copolymer Brushes via Surface Initiated Atom Transfer Radical Copolymerization C. Xu, T. Wu, C. M. Drain, J. D. Batteas, K. L. Beers ACS Polymer Reprints, Fall, 2004.
  • Organizing Self-Assembled Porphyrin Arrays On Metal And Glass Surfaces C.M. Drain, T. Milic, J. C. Garno, G. Smeureanu, J.D. Batteas  ACS Polymer Reprints 2004, 45(1), 346-347.
  • Self-Organization of Self-Assembled Tetrameric Porphyrin Arrays on Surfaces  T. Milic, J. C. Garno, G. Smeureanu, J. D. Batteas, C. M. Drain, Langmuir, 2004, 20, 3974-3983.
  • Self-assembled Porphyrin Arrays on Surfaces C.M. Drain, G. Smeareanu, J.D. Batteas, S. Patel. Book chapter: Dekker Encyclopedia of Nanotechnology, Vol 5. pp3481-3502. J.A. Schwartz, C.I. Contescu, K. Putyera, Eds.; Marcel Dekker, Inc. New York, 2004.
  • A Bench Top Method for the Fabrication and Patterning of Nanoscale Structures on Polymers  J. M. Helt, C. M. Drain, J. D. Batteas, J. Am. Chem. Soc. 136, 2004, 628-634.
  • Self-Assembled Porphyrinic Nanoarchitectures C.M. Drain, X. Chen. Book chapter: Encyclopedia of Nanoscience & Nanotechnology Vol. 9, pp593-616. H.S. Nalwa Edt., American Scientific Press, 2004.

Grants

  • Conbinatorial Chemistry of Porphyrins, NIH 2004 (SCORE) $550K
  • fellowship for graduate student Chang Xu N.I.S.T. 2004:$8K
  • Porphyrin Therapeutics, PSC-CUNY 2003 $4K
  • fellowship graduate N.S.F.-N.I.S.T. 2004 $6.6K
  • Self-Assembled Phonic Materials N.S.F. 2002 $360K
  • Binational Science Foundation, with Israel Goldberg Israel-US 2000: $240K
  • Interdisciplinary Graduate Education Training Research, N.S.F. 1999: IGERT Co-PI ~$1000K/year, 4 years for HC, ~$3.5M for the program